ISOO, MASCC and ASCO have released a new joint guideline for the prevention and management of osteoradionecrosis (ORN) of the jaw secondary to head and neck radiation therapy in patients with cancer. This guideline was created by a multidisciplinary expert panel who evaluated evidence from randomized controlled trials, observational studies, and systematic reviews.
Evidence-based recommendations with strong evidence to support were possible with regards to best practices in prevention and surgical management of ORN; however no recommendations were possible for the utilization of leukocyte- and platelet-rich fibrin or photobiomodulation. The use of hyperbaric oxygen in prevention and management of ORN remains largely unjustified, with limited evidence to support its practice.
Read the full guideline or download a summary of the recommendations below:
