MASCC Guidelines
Evidence-based Clinical Practice Guidelines & Summaries
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Evidence-based clinical practice guidelines created by the MASCC study groups.
To access the full guidelines and guideline summary documents, simply log into your member account (for MASCC members) or provide your email address below (for non-members).
Antiemetics Study Group
MASCC/ESMO consensus recommendations: Anticipatory nausea and vomiting in children and adults receiving chemotherapy (2016 update) – UNDER REVISION
Dupuis LL et al. Supportive Care in Cancer (2016)
MASCC/ESMO consensus recommendations: Controlling nausea and vomiting with chemotherapy of low or minimal emetic potential (2016 update) – UNDER REVISION
Olver I et al. Supportive Care in Cancer (2016)
MASCC/ESMO consensus recommendations: Emetic risk classification and evaluation of the emetogenicity of antineoplastic agents (2016 update) – UNDER REVISION
Jordan K et al. Supportive Care in Cancer (2016)
MASCC/ESMO consensus recommendations: Prevention of acute chemotherapy-induced nausea and vomiting in children (2016 update) – UNDER REVISION
Dupuis LL et al. Supportive Care in Cancer (2016)
MASCC/ESMO consensus recommendations: Prevention of nausea and vomiting following high emetic risk chemotherapy (2016 update) – UNDER REVISION
Herrstedt J et al. Supportive Care in Cancer (2016)
MASCC/ESMO consensus recommendations: Prevention of nausea and vomiting following moderately emetogenic chemotherapy (2016 update) – UNDER REVISION
Roila F et al. Supportive Care in Cancer (2016)
MASCC/ESMO consensus recommendations: Prevention of radiotherapy-induced nausea and vomiting (2016 update) – UNDER REVISION
Ruhlmann CH et al. Supportive Care in Cancer (2016)
Erratum to: 2016 updated MASCC/ESMO consensus recommendations: Prevention of nausea and vomiting following moderately emetogenic chemotherapy
Roila F et al. Supportive Care Cancer (2016)
Summary Slide Set(2016 with updates 2019 - This summary slide set encompasses all of the publications above)
Antiemetics in advanced cancer (MASCC updated guideline)
Davis M et al. Supportive Care in Cancer (2021)
Summary Slide Set(2021)
Summary Document(2021)
Nausea and vomiting in malignant bowel obstruction
Davis M et al. Medical management of malignant bowel obstruction in patients with advanced cancer: 2021 MASCC guideline update. Supportive Care in Cancer (2021)
Summary Slide Set(2021)
Summary Document(2021)
Bone and Musculoskeletal Study Group
Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline
Yarom N et al. Journal of Clinical Oncology (2019)
Summary Slide Set(2019)
Summary Document(2019)
Cancer Pain Subgroup
Cannabis for cancer-related pain and risk of harms and adverse events – NEW
To J et al. Supportive Care in Cancer (2023).
Summary Slide Set(2023)
Summary Document(2023)
De Feo G et al. Supportive Care in Cancer (2023).
Summary Slide Set(2023)
Summary Document(2023)
Alderman B et al. Supportive Care in Cancer (2022).
Summary Slide Set(2022)
Summary Document(2022)
Immuno-Oncology Subgroup
Rapoport BL et al. Supportive Care in Cancer (2020)
Cancer immunotherapy–related adverse events: causes and challenges
Blidner AG et al. Supportive Care in Cancer (2020)
Cooksley T et al. Supportive Care in Cancer (2020)
Suarez-Almazor ME et al. Supportive Care in Cancer (2020)
Shannon VR et al. Supportive Care in Cancer (2020)
Choi J et al. Supportive Care in Cancer (2020)
Mucositis Study Group
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Summary – Original article
MASCC/ISOO clinical practice guidelines for the management of mucositis secondary to cancer therapy
Elad S et al. Cancer (2020)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Guideline Summary Translations – Available in Arabic, French, German, Greek, Japanese, Portuguese (Brazil and Portugal dialects) and Spanish.
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Introduction to part 1
The MASCC/ISOO Mucositis Guidelines 2019 Update: introduction to the first set of articles
Elad S. Supportive Care in Cancer (2019)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Introduction to part 2
The MASCC/ISOO Mucositis Guidelines 2019: the second set of articles and future directions
Elad S. Supportive Care in Cancer (2020)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Methods
Development of the MASCC/ISOO clinical practice guidelines for mucositis: an overview of the methods
Ranna V et al. Supportive Care in Cancer (2019)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Basic oral care
Systematic review of basic oral care for the management of oral mucositis in cancer patients and clinical practice guidelines
Hong CHL et al. Supportive Care in Cancer (2019)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Photobiomodulation therapy / laser
Systematic review of photobiomodulation for the management of oral mucositis in cancer patients and clinical practice guidelines
Zadik Y et al. Supportive Care in Cancer (2019)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version))
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Anti-inflammatory agents
Systematic review of anti-inflammatory agents for the management of oral mucositis in cancer patients and clinical practice guidelines
Ariyawardana A et al. Supportive Care in Cancer (2019)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Natural and miscellaneous agents – Part 1
Systematic review of natural and miscellaneous agents for the management of oral mucositis in cancer patients and clinical practice guidelines-part 1: vitamins, minerals, and nutritional supplements
Yarom N et al. Supportive Care in Cancer (2019)
Summary Slide Set (2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Natural and miscellaneous agents – Part 2
Systematic review of natural and miscellaneous agents, for the management of oral mucositis in cancer patients and clinical practice guidelines – part 2: honey, herbal compounds, saliva stimulants, probiotics, and miscellaneous agents
Yarom N et al. Supportive Care in Cancer (2020)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Antimicrobials, mucosal coating agents, anesthetics, and analgesics
Systematic review of antimicrobials, mucosal coating agents, anesthetics, and analgesics for the management of oral mucositis in cancer patients and clinical practice guidelines
Saunders DP et al. Supportive Care in Cancer (2020)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Cryotherapy
Systematic review of oral cryotherapy for the management of oral mucositis in cancer patients and clinical practice guidelines
Correa MEP et al. Supportive Care in Cancer (2019)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – Growth factors and cytokines
Systematic review of growth factors and cytokines for the management of oral mucositis in cancer patients and clinical practice guidelines
Logan RM et al. Supportive Care in Cancer (2020)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – all interventions for GI mucositis
Systematic review of agents for the management of cancer treatment-related gastrointestinal mucositis and clinical practice guidelines
Bowen JM et al. Supportive Care in Cancer (2019)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – sub-analysis: all interventions in pediatric patients
MASCC/ISOO clinical practice guidelines for the management of mucositis: sub-analysis of current interventions for the management of oral mucositis in pediatric cancer patients
Miranda-Silva W et al. Supportive Care in Cancer (2020)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – systematic review – pathogenesis
The pathogenesis of mucositis: updated perspectives and emerging targets
Bowen J et al. Supportive Care in Cancer (2019)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Mucositis Study Group, MASCC/ISOO mucositis guidelines – systematic review – risk prediction
Prediction of mucositis risk secondary to cancer therapy: a systematic review of current evidence and call to action
Wardill HR et al. Supportive Care in Cancer (2020)
Summary Slide Set(2019 - 2020 version)
Summary Document(2019 - 2020 version)
Oncodermatology Study Group
Behroozian et al. eClinicalMedicine (2023).
Behroozian et al. Lancet Oncology (2023).
Summary Slides(2023)
Summary Document(2023)
Clinical practice guidelines for the prevention and treatment of EGFR inhibitor-associated dermatologic toxicities – UNDER REVISION
Lacouture ME et al. Supportive Care in Cancer (2011)
Summary Slide Set(2011)
Oral Care Study Group
Management of oral problems in patients with advanced cancer (MASCC/ISOO expert opinion)
Jones JA et al. Supportive Care in Cancer (2022)
Summary Slide Set(2022)
Summary Document(2022)
Salivary gland hypofunction and/or xerostomia induced by nonsurgical cancer therapies (ISOO/MASCC/ASCO Guideline)
Mercadante V et al. Supportive Care in Cancer (2021)
Summary Slide Set(2021)
Summary Document(2021)
Medication-Related Osteonecrosis of the Jaw: MASCC/ISOO/ASCO Clinical Practice Guideline
Yarom N et al. Journal of Clinical Oncology (2019)
Summary Slide Set(2019)
Summary Document(2019)
Palliative Care Study Group
Management of oral problems in patients with advanced cancer (MASCC/ISOO expert opinion)
Jones JA et al. Supportive Care in Cancer (2022)
Summary Slide Set(2022)
Summary Document(2022)
Management of malignant bowel obstruction in advanced cancer (MASCC multidisciplinary evidence-based recommendations)
Madariaga A et al. Supportive Care in Cancer (2022)
Antiemetics in advanced cancer (MASCC updated guideline)
Davis M et al. Supportive Care in Cancer (2021)
Summary Slide Set(2021)
Summary Document(2021)
Nausea and vomiting in malignant bowel obstruction
Davis M et al. Medical management of malignant bowel obstruction in patients with advanced cancer: 2021 MASCC guideline update. Supportive Care in Cancer (2021)
Summary Slide Set(2021)
Summary Document(2021)
The use of clinically assisted nutrition in patients with advanced cancer (MASCC expert opinion/guidance)
Alderman B et al. Supportive Care in Cancer (2021)
Summary Slide Set(2021)
Summary Document(2021)
Endorsed Guidelines
Exercise Oncology
Exercise recommendation for people with bone metastases: Expert consensus for health care providers and exercise professionals
Campbell KL et al. JCO Oncology Practice (2022)
Endorsed by the Exercise Oncology Subgroup (Hart NH et al. Supportive Care in Cancer 2022)
Pediatrics
Prevention of acute and delayed chemotherapy-induced nausea and vomiting in pediatric cancer patients: A clinical practice guideline
Patel P et al. Pediatric Blood Cancer (2022)
Endorsed by the Pediatrics Study Group